1 Corinthians 13:2
"Proteins are the fundamental building blocks of life, carrying out a vast range of functions in the cell. Their functions depend critically on their three-dimensional structures, which arise from the way a sequence of amino acids folds.
"Proteins are the fundamental building blocks of life, carrying out a vast range of functions in the cell. Their functions depend critically on their three-dimensional structures, which arise from the way a sequence of amino acids folds.
The process by which a protein arrives at its functional shape isknown as protein folding, and for decades, it has been one of the most complex unsolved problems in biology. Scientists have sought to predict protein structures from their amino acid sequences—what is known as “the protein folding problem.”
Take X-ray crystallography, for example.
Take X-ray crystallography, for example.
Here the target protein is purified and coaxed into forming a crystalline structure, an arduous process that can take weeks, months,or even years for some proteins. And not all proteins are cooperative — some simply refuse to crystallize, rendering them nearly invisible to this technique. But for those that do, the results can be remarkable. Once crystallized, the sample is bombarded with high-energy X-rays, and the resulting diffraction patterns are analyzed to reconstruct the molecule’s atomic arrangement.
X-ray crystallography was famously used in the 1950s to help uncover the double-helix structure of DNA, an achievement that fundamentally reshaped our understanding of genetics. Since then, crystallography has illuminated the structures of countless biological molecules, from enzymes to viral proteins, laying the foundation for modern molecular biology."
X-ray crystallography was famously used in the 1950s to help uncover the double-helix structure of DNA, an achievement that fundamentally reshaped our understanding of genetics. Since then, crystallography has illuminated the structures of countless biological molecules, from enzymes to viral proteins, laying the foundation for modern molecular biology."
MindMatters