.....since the day that God created man upon the earth,
Deuteronomy 4:32
"Scientists have long been baffled as to what actually tells proteins called transcription factors (TFs) where to bind in the genome to turn genes off and on. However, new research incorporating the three-dimensional shape of DNA has revealed an incredibly complex system of interacting biochemical codes.We know that genes are turned off and on across the genome by intricate networks of transcription factors which bind to DNA in strategic places in and around the genes. But discovering what tells the transcription factors where to bind has proven extremely difficult.
But the new research has revealed that two main things influence how DNA is read by transcription factors:
- the actual sequence of the DNA and,
- the conformational shape of the DNA as it's being read.
DNA is a double-stranded string of four different molecules called nucleotide bases (represented by the letters A, T, G, and C). The interdependence between nucleotide positions stems from the physical interactions between base pairs. These interactions give rise to the 3D structure of DNA which in turn helps transcription factors recognize specific sites for binding.
Yet another noteworthy feature of this new report is the fact that the failed theory of evolution was not given any credit whatsoever for accomplishing any of this amazing complexity. Obviously, to do so would have been utterly absurd—a type of oxymoron. The clear deduction from this surprising discovery—which required a combination of complex biochemistry and interpretive computer algorithms—is that an omnipotent Creator engineered it all in the beginning." ICR