Psalm 139:14 NLT".....various obstacles to the evolutionary origins of the glycolytic pathway. As noted previously, the end result of glycolysis is pyruvate.
---Pyruvate is then transported into the mitochondria where it is converted into acetyl-CoA by the enzyme pyruvate dehydrogenase.
---This process also produces NADH and releases one molecule of carbon dioxide (CO2).
---The acetyl-CoA then feeds into the Krebs cycle (also known as the citric acid or tricarboxylic acid cycle), where it is further oxidized, generating more NADH, FADH2, and ATP (or GTP).
---Pyruvate is also converted to oxaloacetate in a reaction catalyzed by the enzyme pyruvate carboxylase. Acetyl-CoA then combines with oxaloacetate in the Krebs cycle to form citrate.
The final yield, per turn of the Krebs cycle is 3 NADH, 1 FADH2, 1 GTP (or ATP), and 2 CO2. Since each glucose molecule produces two molecules of acetyl CoA (from two pyruvate molecules), the results of the Krebs cycle per molecule of glucose are 6 NADH, 2 FADH2, 2 GTP (or ATP), and 4 CO2. The NADH and FADH2 are important because they carry high-energy electrons to the electron transport chain, where they help produce more ATP. Carbon dioxide (CO2) is released as a waste product. The Krebs cycle requires the presence of at least nine enzymes, as well as three cofactors."
The final yield, per turn of the Krebs cycle is 3 NADH, 1 FADH2, 1 GTP (or ATP), and 2 CO2. Since each glucose molecule produces two molecules of acetyl CoA (from two pyruvate molecules), the results of the Krebs cycle per molecule of glucose are 6 NADH, 2 FADH2, 2 GTP (or ATP), and 4 CO2. The NADH and FADH2 are important because they carry high-energy electrons to the electron transport chain, where they help produce more ATP. Carbon dioxide (CO2) is released as a waste product. The Krebs cycle requires the presence of at least nine enzymes, as well as three cofactors."
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