"The Most Holy Place was entered only on the day of atonement.
Lev.16:2,29,30; Heb.9:7
--And the LORD said unto Moses, Speak unto Aaron thy brother, that he come not at 
all times into the holy place within the vail before the mercy seat, which is upon the ark; that he die not: for I will appear in the cloud upon the mercy seat....And this shall be a statute for ever unto you: that in the seventh month, on the tenth day of the month, ye shall afflict your souls, and do no work at all, whether it be one of your own country, or a stranger that sojourneth among you: For on that day shall the priest make an atonement for you, to cleanse you, that ye may be clean from all your sins before the LORD......But into the second went the high priest alone once every year, not without blood, which he offered for himself, and for the errors of the people:....
Note:- Making the atonement, and cleansing the sanctuary are identical.
*From Rev.15:8 (And the temple was filled with smoke from the glory of God, and from his power; and no man was able to enter into the temple, till the seven plagues of the seven angels were fulfilled.), we learn that when the plagues, threatened in the Third Angel's Message, [Rev.14:9-11,] and described in Chap. 16, are poured out, there will be no ministration: therefore they are "poured out without mixture," as the mediation of Christ will then have ceased, and mercy will no more be offered to sinners."
Uriah Smith
