For we know that the whole creation groaneth and travaileth in pain together ....
Romans 8:22
"Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells.
The search for effective nanobodies — which are fragments of antibodies that occur naturally in camelids and can be adapted for humans — began in February when an alpaca was injected with the new coronavirus’ spike protein, which is used to enter our cells. After 60 days, blood samples from the alpaca showed a strong immune response against the spike protein.
They identified one, Ty1 (named after the alpaca Tyson), that efficiently neutralizes the virus by attaching itself to the part of the spike protein that binds to the receptor ACE2, which is used by SARS-CoV-2 to infect cells. This blocks the virus from slipping into the cells and thus prevents infection. “Our results show that Ty1 can bind potently to the SARS-CoV-2 spike protein and neutralize the virus, with no detectable off-target activity” says Ben Murrell.
The sequence of Ty1 is available in the scientific article and will also be posted on the NCBI GenBank sequence database under the accession code MT784731."
SciTechDaily
Romans 8:22
"Researchers at Karolinska Institutet in Sweden have identified a small neutralizing antibody, a so-called nanobody, that has the capacity to block SARS-CoV-2 from entering human cells.
The search for effective nanobodies — which are fragments of antibodies that occur naturally in camelids and can be adapted for humans — began in February when an alpaca was injected with the new coronavirus’ spike protein, which is used to enter our cells. After 60 days, blood samples from the alpaca showed a strong immune response against the spike protein.
They identified one, Ty1 (named after the alpaca Tyson), that efficiently neutralizes the virus by attaching itself to the part of the spike protein that binds to the receptor ACE2, which is used by SARS-CoV-2 to infect cells. This blocks the virus from slipping into the cells and thus prevents infection. “Our results show that Ty1 can bind potently to the SARS-CoV-2 spike protein and neutralize the virus, with no detectable off-target activity” says Ben Murrell.
The sequence of Ty1 is available in the scientific article and will also be posted on the NCBI GenBank sequence database under the accession code MT784731."
SciTechDaily
