"For decades, evolutionary biology assured us that DNA was essentially a linear code: a long string of chemical letters shaped by mutation and natural selection. The sequence mattered; the rest was secondary, and a great deal of it was “junk,” supposedly useless leftovers from millions of years of evolutionary processes.
That picture has quietly but catastrophically collapsed.
"Scientists have created the most detailed maps yet of how human DNA folds, loops, and shifts inside living cells — revealing a hidden layer of genetic control."
Under the umbrella of the National Institute of Health’s 4D
--DNA is not just a string of text,
--but also a dynamic, origami-like architecture,
--folding into precisely bounded domains whose shapes change over time.
Reading DNA sequences alone was not enough. Something deeper had to be mapped: the four-dimensional architecture that makes the information-sequence functional.
The DNA molecule is more like a factory – more accurately, a Grand Factory consisting of a collection of smaller, nested modular factories."
CEH
