“Psalm 6:1 Rebuke me not in Thine anger:
(verse 1), indicates that David is conscious of deserving rebuke.However, he prays, as always, “Have mercy upon me, O Lord” (verse 2).
The miseries of the depressed are both physical and psychological, and often the description of the two conditions is interwoven (verse 2-3).
“In the grave who shall give Thee thanks”:
(Verse 5), serves to remind the LORD that David’s continued praise and witness depend on his preservation.
David’s cries, coming up from the depths of his personal pit of persecution, indicate a radical change in his frame of mind as he addresses two different audiences.
(1) Pouring out His Soul before God: A defeatist Frame of Mind (6:1-7).
A.A tone of Helplessness (6:1-4);
B.A tone of Hopelessness (6:5-7).
(2)Turning His Attention to His Enemies: A Defiant Frame of Mind (6:8-10).
A. His Boldness about it (6:8a);
B. His Basis for it (6:8b-10).
Psalm 6 is the first of the penitential psalms (6; 32; 38; 51; 102;130; 143).
David prays the words of this psalm when he is deeply troubled by something, possibly an illness that his own sin may have caused (41:4; Hosea 6:1).
“Mercy”:
In this situation is not deserved but urgently needed.
“My bones” and “my soul” represent the whole person." BooksOfTheBible

