Thank You for making me so wonderfully complex!
Your workmanship is marvelous—how well I know it.
Psalm 139:14 NLT
"Every cell in your body contains the same genetic sequence,
---yet each cell expresses only a subset of those genes.
These cell-specific gene expression patterns, which ensure that a
brain cell is different from a skin cell, are partly determined by the three-dimensional structure of the genetic material, which controls the accessibility of each gene.
Inside the cell nucleus, DNA and proteins form a complex called chromatin, which has several levels of organization,
Inside the cell nucleus, DNA and proteins form a complex called chromatin, which has several levels of organization,
---allowing cells to cram 2 meters of DNA into a nucleus that is only one-hundredth of a millimeter in diameter.
Long strands of DNA wind around proteins called histones, giving rise to a structure somewhat like beads on a string.
Chemical tags known as epigenetic modifications can be attached to DNA at specific locations, and these tags, which vary by cell type, affect the folding of the chromatin and the accessibility of nearby genes.
Chemical tags known as epigenetic modifications can be attached to DNA at specific locations, and these tags, which vary by cell type, affect the folding of the chromatin and the accessibility of nearby genes.
These differences in chromatin conformation help determine which genes are expressed in different cell types, or at different times within a given cell."
Phys.org
