1 Corinthians 1:27
"Scientists have debunked a notion that during development a “second brain” emerges from the neural crest that runs the gut. The gut is lined with neurons called the “enteric nervous system” (ENS) that tells the brain when we are hungry, full, or have indigestion. But does it come from the neural crest in the embryo? Prepare for decades of dogma to be thrown out the window.
Since the mid-20th century, scientists have believed that the ENS isderived from the neural crest before birth and remains unchanged after.
"Scientists have debunked a notion that during development a “second brain” emerges from the neural crest that runs the gut. The gut is lined with neurons called the “enteric nervous system” (ENS) that tells the brain when we are hungry, full, or have indigestion. But does it come from the neural crest in the embryo? Prepare for decades of dogma to be thrown out the window.
Since the mid-20th century, scientists have believed that the ENS isderived from the neural crest before birth and remains unchanged after.
Now, in a paper published in the journal eLife, researchers at Beth Israel Deaconess Medical Center (BIDMC) present a completely new paradigm describing a developmental pathway by which ENS development continues after birth in mice and human tissue samples.
This discovery overturns decades of scientific dogma on the fundamental biology of neuroscience and of ENS, by showing evidence for the first time of a non-ectodermal and a mesodermal origin for large numbers of enteric neurons born after birth.
The findings show the relevance of these neurons to the maturation and aging of the ENS in health and disease." CEH