Genetic mutations
"Evolution needs to incorporate massive amounts of new genetic information for organisms to evolve from simple cells to complex living organisms over millions of years.However, what the evidence shows is that mutations are neutral at best.
Sometimes mutations only transfer genetic information between two positions in the genome.
At worst mutations destroy information.
According to simulations, mutations cannot build up even small amounts of the genetic information required for macroevolution.
Ultimately, mutations are copying mistakes in the instructions for making complex organisms. It is rare that a complexity is improved by breaking the instructions for making the machine."
CMI
For we know that the whole creation groaneth and travaileth in pain together until now.
Romans 8:22