From Babel to Japan

Therefore is the name of it called Babel; because the LORD did there confound the language of all the earth: and from thence did the LORD scatter them abroad upon the face of all the earth. Genesis 11:9

Apparently, on their trek from Babel, the group that became the East Asian Orientals branched into Japan in 3 waves. They also mated with Neanderthals and Denisovans (simply another developed

species of humans) along the trek. It also seems that the Neanderthals and Denisovans had developed genetic defects early on and passed them on into the populations they came into contact with.
It may be that a very small groupings of humans developed some serious defects in their genome very early on as they spread out resulting in the differences we know as Neanderthals and Denisovans. This in turn led to them spanning out from others early on in different directions, keeping to themselves until bumping again into the dominate human lineage.

"Scientists analyzing the genomes of thousands of people across Japan discovered evidence for a previously overlooked third ancestral group, challenging the long-accepted “dual origins” theory. The newly identified ancestry appears linked to the ancient Emishi

people of northeastern Japan. Researchers also uncovered inherited
Neanderthal and Denisovan DNA.
The findings emerged from the JEWEL (Japanese Whole-genome sequencing Evaluation of Large-scale data) project, which produced high-depth genome sequences for participants sampled from prefectures across Japan.

For decades, scientists believed the Japanese population largely descended from two ancient groups: the Jomon hunter-gatherers who lived in the archipelago for thousands of years, and later migrants from East Asia who brought rice farming and new technologies to Japan.
But a major genetic analysis from researchers at RIKEN's Center for Integrative Medical Sciences suggests the picture is far more

complicated.
Using whole-genome sequencing on more than 3,200 people from across Japan, the team found evidence supporting a third ancestral group tied to northeastern Asia and possibly linked to the ancient Emishi people. The findings, published in Science Advances, add powerful support to the increasingly discussed "tripartite origins" theory of Japanese ancestry.

The discovery means that modern Japanese ancestry is not a blend of two source populations but three, each arriving in a distinct historical wave.
Those three clusters map onto distinct regions of the archipelago. One is centered on Okinawa and enriched in Jomon ancestry,

reflecting the deep heritage of the Ryukyu Islands. 

A second dominates western Japan, particularly the Kansai region around Osaka and Kyoto, and carries a stronger signal of continental migration. 

The third, the new finding, is concentrated in the Tohoku region of northeastern Honshu. It does not collapse neatly into either the Jomon or the Yayoi category. Instead, it appears to represent a separate strand of ancestry with its own history.
The study also explored genetic material inherited from Neanderthals and Denisovans, two ancient human groups that interbred with Homo sapiens.

Scientists have become increasingly interested in why some of these ancient DNA fragments survived in modern humans while others disappeared. In many cases, the inherited genes appear linked to health, adaptation, or disease risk.

The Japanese genome study identified 44 archaic DNA regions still present in modern Japanese populations, many of them unique to East Asians. 

One Denisovan-derived region inside the NKX6-1 gene was associated with type 2 diabetes and may influence how some patients respond to semaglutide treatments.
Researchers also found 11 Neanderthal-derived genetic segments connected to conditions including coronary artery disease, prostate cancer, and rheumatoid arthritis.
SD/msn

For we know that the whole creation groaneth and travaileth in pain together until now.
Romans 8:22