And they of the south shall possess the mount of Esau;
and they of the plain the Philistines:
and they shall possess the fields of Ephraim,
and the fields of Samaria: and Benjamin shall possess Gilead.
Obadiah 1:19
"Edom lay to the south;
the Philistines to the west,
Ephraim to the north;
and Gilead to the east.
Those who returned from Babylon were to extend themselves everywhere."
Adam Clarke's Commentary
In other words....
And I heard another voice from heaven, saying,
Come out of her, my people,
that ye be not partakers of her sins, and that ye receive not of her plagues.
Revelation 18:4
...Form the 4 cardinal directions....
And they shall come from the east,
and from the west,
and from the north,
and from the south,
and shall sit down in the kingdom of God.
Luke 13:29