Commentary of Charles Spurgeon, Adam Clarke & Matthew Henry
He is despised and rejected of men; 
a man of sorrows,
and acquainted with grief:
and we hid as it were our faces from him;
he was despised, and we esteemed him not.
Vs.3
We hid as it were our faces from him --- Mourners covered up the lower part of their faces, and their heads, 2 Samuel 15:30; Ezekiel 
29:17; and lepers were commanded by the law, Leviticus 13:45, to cover their upper lip.
It
may be read, He hid as it were his face from us, concealed the glory of
his majesty, and drew a veil over it, and therefore he was despised and we
esteemed him not, because we could not see through that veil.
Christ having
undertaken to make satisfaction to the justice of God for the injury man had
done him in his honor by sin (and God cannot be injured except in his honor),
--he did it not only by divesting himself of the glories due to an incarnate
deity,
--but by submitting himself to the disgraces due to the worst of men and
malefactors;
--and thus by vilifying himself he glorified his Father:
--but this is
a good reason why we should esteem him highly,
--and study to do him honor; let him
be received by us whom men rejected.
Men, who should have had so much reason as to understand things better, so
much tenderness as not to trample upon a man in misery—men whom he came to
seek and save rejected him.
