Tuesday, August 29, 2023

Creation Moment 8/30/2023 - "Humbling"

Thank you for making me so wonderfully complex!
Your workmanship is marvelous... 
Psalm 139:14

"Life runs on ribosomes. 
Every cell across the globe requires ribosomes to convert genetic data into the vital proteins required for the organism’s operation, and, subsequently, for the production of more ribosomes. 
However, scientists still lack a clear understanding of
how these essential nanomachines are assembled.
Now, new high-resolution images of the large ribosomal subunit are shedding light on how arguably nature’s most fundamental molecule coalesces in human cells. 
The findings, published in Science, bring us one step closer to a complete picture of ribosome assembly. Klinge and colleagues focused on the human large ribosomal subunit (60S). The team already knew, from studies in yeast, that the large subunit’s formation involves two precursors (a 5S rRNA and 32S pre-rRNA) snapping together, but “we wanted to know all of the events that need to happen for this to occur,” says Arnaud Vanden Broeck, a postdoctoral researcher in Klinge’s lab.
We wanted to explain how the large subunit is assembled and processed in human cells.” 
Klinge and Vanden Broeck are content to marvel at the substantial leap forward. “It’s not guesswork anymore,” Klinge says. “We can now see, in detail, what’s going on when the large subunit assembles. It’s humbling to realize we’re finally able to see what makes ribosomes and drives protein formation in all of our own cells.” 
SciTechDaily