I will praise thee; for I am fearfully and wonderfully made... Psalm 139:14
The introns lie between the exons.
The whole gene is
copied to RNA and then edited to remove the introns (‘spliced’ with a
phenomenally complex machine called a
‘spliceosome’) to produce the protein-coding
mRNA—or so it was thought.
This study of brain tissue reinforces that different mRNAs can be
produced in various ways.
Most commonly the splicing skips the first
exon, or skips another exon, or includes an intron or uses an
alternative last exon from another gene (in that order of frequency).
Overall, the researchers found that over half of the genes produced more
than one mRNA. Some produced mRNA transcripts for more than ten
different proteins.
All this adds up to amazing complexity in the regulation of the
genes.
Q: How do the cells decide how to edit each RNA (which protein to
produce, and how much)?
The mind boggles at the sophistication of the divine design that researchers are uncovering day by day." CMI