For the wisdom of this world is foolishness with God.
1 Corinthians 3:19
"......scientists have attempted to determine the simplest self-reproducing cell.
This hypothetical cell was said to require a minimum of 256 genes.
The
problem for evolutionists is that they cannot appeal to natural
selection to explain the first cell.
---That’s because natural selection
requires a living, reproducing cell to pass on any trait selected for!
Further research in 2006 increased this figure to 387 protein-coding 
and
43 RNA-coding genes.
In 2016, the minimalist genome was once again increased with the creation of a synthetic self-reproducing bacterium: this time, to 473 genes (531,560 ‘letters’), including 65 whose function are unknown but which were essential for the survival of the cell.
This is not much less
than Mycoplasma genitalium (482 genes, 582,970 letters)—which
itself is a parasite of even more complex organisms.
Q: How then can
evolutionists explain the origin of the very first self-reproducing
cell?
----It is a mathematical impossibility for just one gene to have
arisen by chance—much less 473." CMI