For we know that the whole creation groaneth and travaileth in pain together until now.
Romans 8:22
As the human race races towards 0.4/Ne. T, the opposite of
evolution is happening.....but if we began fully operational at Creation, then began degeneration sometime after, then the path towards 0.4/Ne. T is what we would, and do, see....
".... the value of a selection coefficient (impact on fitness by a mutation) greatly impacts the decrease in fitness from mutation accumulation:
“It is now well established that
---mutations with small, but intermediate, deleterious effects cause the most cumulative damage to populations (Kimura, Gabriel, Charlesworth).
---Mutations with very large effects are eliminated efficiently by selection and have essentially no chance of fixation,
---whereas neutral mutations have no influence on individual fitness.
The diffusion theory developed by Lande (1994) suggests that the value of s that minimizes the time to extinction, that is, that does the most damage, is s* = 0.4/Ne. T” CEV
Romans 8:22
As the human race races towards 0.4/Ne. T, the opposite of
".... the value of a selection coefficient (impact on fitness by a mutation) greatly impacts the decrease in fitness from mutation accumulation:
“It is now well established that
---mutations with small, but intermediate, deleterious effects cause the most cumulative damage to populations (Kimura, Gabriel, Charlesworth).
---Mutations with very large effects are eliminated efficiently by selection and have essentially no chance of fixation,
---whereas neutral mutations have no influence on individual fitness.
The diffusion theory developed by Lande (1994) suggests that the value of s that minimizes the time to extinction, that is, that does the most damage, is s* = 0.4/Ne. T” CEV