The 1st sermon preached by John Knox (founder of the Presbyterian Church) was on the 4 beasts of Daniel ending with the Little Horn being the Papacy.
I considered the horns, and, behold,
there came up among them another little horn,
before whom there were three of the first horns plucked up by the roots:
and, behold,
in this horn were eyes like the eyes of man,
and a mouth speaking great things.
Daniel 7:8