"In simple words, [it] says that the net change of a smooth and continuous quantity, such as a distance travelled, over a given time interval (i.e. the difference in the values of the quantity at the end points of the time interval) is equal to the integral of the rate of change of that quantity, i.e. the integral of the velocity," said Melkana Brakalova-Trevithick, chair of the math department at Fordham University.
The seeds of calculus began in ancient times, but much of it was put together in the 17th century by Isaac Newton, who used calculus to describe the motions of the planets around the sun." LiveScience
* It should be noted that Newton wrote MORE on Bible prophecy than science & mathematics---he was using science & mathematics to observe God's creation--& how it operates.
And he hath filled him with the spirit of God,
in wisdom,
in understanding,
and in knowledge,
Exodus 35:31